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The IS 300 is a good car, but its competitors are better.
Does the glovebox need to be removed? Unfortunately, the Lexus IS 300 competes against a bunch of really great options.
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Our navigation function has nothing to do with the factory navigation system.
In other words does the choice to go with factory nav or not mean anything? If you don't need the added traction of all-wheel drive, I say stick with the RWD IS 300 or upgrade to the RWD IS 350, simply because of the more modern eight-speed transmission.