Sometimes, lymph nodes near the ulcer become enlarged, but remain painless.
Upon arrival in the Old World, the bacterium, which was similar to modern day yaws, responded to new selective pressures with the eventual birth of the subspecies of sexually transmitted syphilis.
The Economic History Review.
Retrieved 14 December 2021.
The genitals are the most common location for chancres to develop, but these ulcers also can form around the mouth or anus.
The goal of mercury treatment was to cause the patient to salivate, which was thought to expel the disease.